DRY EYE



What is dry eye?
Dry eye occurs when the eye does not produce tears properly, or when the tears are not of the correct consistency and evaporate too quickly.

In addition, inflammation of the surface of the eye may occur along with dry eye. If left untreated, this condition can lead to pain, ulcers, or scars on the cornea, and some loss of vision. However, permanent loss of vision from dry eye is uncommon.

Dry eye can make it more difficult to perform some activities, such as using a computer or reading for an extended period of time, and it can decrease tolerance for dry conditions, such as the air inside an airplane or air conditioned environments).

 

Dry eye can be associated with:

  • inflammation of the surface of the eye, the lacrimal gland, or the conjunctiva;
  • any disease process that alters the components of the tears;
  • an increase in the surface of the eye, as in thyroid disease when the eye protrudes forward;
  • cosmetic surgery, if the eyelids are opened too widely.

SYMPTOMS

What are the symptoms of dry eye?
Dry eye symptoms may include any of the following:

  • stinging or burning of the eye;
  • a sandy or gritty feeling as if something is in the eye;
  • episodes of excess tears following very dry eye periods;
  • a stringy discharge from the eye;
  • pain and redness of the eye;
  • episodes of blurred vision;
  • heavy eyelids;
  • inability to cry when emotionally stressed;
  • uncomfortable contact lenses;
  • decreased tolerance of reading, working on the computer, or any activity that requires sustained visual attention;
  • eye fatigue.

NOTE: If symptoms of dry eye persist, consult an eye care professional to get an accurate diagnosis of the condition and begin treatment to avoid permanent damage.

CAUSES AND RISK FACTORS

What are the causes of dry eye?

Dry eye can be a temporary or chronic condition:

Dry eye can be a side effect of some medications, including antihistamines, nasal decongestants, tranquilizers, certain blood pressure medicines, Parkinson's medications, birth control pills and anti-depressants.

Skin disease on or around the eyelids can result in dry eye.

Diseases of the glands in the eyelids, such as meibomian gland dysfunction, can cause dry eye.

Dry eye can occur in women who are pregnant.

Women who are on hormone replacement therapy may experience dry eye symptoms. Women taking only estrogen are 70 percent more likely to experience dry eye, whereas those taking estrogen and progesterone have a 30 percent increased risk of developing dry eye.

Dry eye can also develop after the refractive surgery known as LASIK. These symptoms generally last three to six months, but may last longer in some cases.

Dry eye can result from chemical and thermal burns that scar the membrane lining the eyelids and covering the eye.

Allergies can be associated with dry eye.

Infrequent blinking, associated with staring at computer or video screens, may also lead to dry eye symptoms.

Both excessive and insufficient dosages of vitamins can contribute to dry eye.

Homeopathic remedies may have an adverse impact on a dry eye condition.

Loss of sensation in the cornea from long-term contact lens wear can lead to dry eye.

Dry eye can be associated with immune system disorders such as Sjögren's syndrome, lupus, and rheumatoid arthritis. Sjögren's leads to inflammation and dryness of the mouth, eyes, and other mucous membranes. It can also affect other organs, including the kidneys, lungs and blood vessels.

Dry eye can be a symptom of chronic inflammation of the conjunctiva, the membrane lining the eyelid and covering the front part of the eye, or the lacrimal gland. Chronic conjunctivitis can be caused by certain eye diseases, infection, exposure to irritants such as chemical fumes and tobacco smoke, or drafts from air conditioning or heating.

If the surface area of the eye is increased, as in thyroid disease when the eye protrudes forward or after cosmetic surgery if the eyelids are opened too widely, dry eye can result.

Dry eye may occur from exposure keratitis, in which the eyelids do not close completely during sleep.

Who is likely to develop dry eye?
Elderly people frequently experience dryness of the eyes, but dry eye can occur at any age. Nearly five million Americans 50 years of age and older are estimated to have dry eye. Of these, more than three million are women and more than one and a half million are men. Tens of millions more have less severe symptoms. Dry eye is more common after menopause. Women who experience menopause prematurely are more likely to have eye surface damage from dry eye.

 

TREATMENT

How is dry eye treated?
Depending on the causes of dry eye, your doctor may use various approaches to relieve the symptoms.

Dry eye can be managed as an ongoing condition. The first priority is to determine if a disease is the underlying cause of the dry eye. If it is, then the underlying disease needs to be treated.

Artificial tears, gels, gel inserts, and ointments - available over the counter - as the first line of therapy. They offer temporary relief and provide an important replacement of naturally produced tears in patients with aqueous tear deficiency. Avoid artificial tears with preservatives if you need to apply them more than four times a day or preparations with chemicals that cause blood vessels to constrict.

Cyclosporine, an anti-inflammatory medication, is the only prescription drug available to treat dry eye. It decreases corneal damage, increases basic tear production, and reduces symptoms of dry eye. It may take three to six months of twice-a-day dosages for the medication to work. In some cases of severe dry eye, short term use of corticosteroid eye drops that decrease inflammation is required.

If dry eye results from taking a medication, your doctor may recommend switching to a medication that does not cause the dry eye side effect.

If contact lens wear is the problem, your eye care practitioner may recommend another type of lens or reducing the number of hours you wear your lenses. In the case of severe dry eye, your eye care professional may advise you not to wear contact lenses at all.

Punctal Plugs- Another option is to plug the drainage holes (tear ducts), which are the small circular openings at the inner corners of the eyelids where tears drain from the eye into the nose. Punctal plugs, can be inserted painlessly by an eye care professional. The patient usually does not feel them. These plugs are made of silicone or collagen, are reversible, and are a temporary measure. In severe cases, permanent plugs may be considered.

In some cases, a simple minor procedure, called Punctal Cautery, is recommended to permanently close the drainage holes. The procedure helps keep the limited volume of tears on the eye for a longer period of time.

In some patients with dry eye, supplements or dietary sources (such as tuna fish) of Omega-3 fatty acids (especially DHA and EPA) may decrease symptoms of irritation. The use and dosage of nutritional supplements and vitamins should be discussed with your primary medical doctor.

What can I do to help myself?

Wearing glasses or sunglasses that fit close to the face (wrap around shades) or that have side shields can help slow tear evaporation from the eye surfaces. Indoors, an air cleaner to filter dust and other particles helps prevent dry eyes. A humidifier also may help by adding moisture to the air.

Avoid dry conditions and allow your eyes to rest when performing activities that require you to use your eyes for long periods of time. Instill lubricating eye drops while performing these tasks.


The National Eye Institute (NEI) is part of the National Institutes of Health (NIH) and is the Federal government's lead agency for vision research that leads to sight-saving treatments and plays a key role in reducing visual impairment and blindness.